Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 7/20 | 0.73 |
| ▸ | CA12 | O43570 | 10/20 | 0.54 |
| ▸ | CA1 | P00915 | 10/20 | 0.54 |
| ▸ | CA2 | P00918 | 10/20 | 0.54 |
| ▸ | CA4 | P22748 | 10/20 | 0.54 |
| ▸ | CA9 | Q16790 | 10/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13398726 | 0.93 | PTGER2 (0.63) | PTGER2CA12CA1CA2CA4 | |
| Hydrochloric Acid SCHEMBL5046815 | 0.89 | PTGER2 (0.84) | PTGER2CA12CA1CA2CA4 | |
| SCHEMBL13399133 | 0.88 | PTGER2 (0.75) | PTGER2CA12CA1CA2CA4 | |
| SCHEMBL5050278 | 0.88 | PTGER2 (0.60) | PTGER2CA12CA1CA2CA4 | |
| SCHEMBL6058696 | 0.86 | PTGER2 (0.66) | PTGER2CA12CA1CA2CA4 | |
| Hydrochloric Acid SCHEMBL5046618 | 0.86 | PTGER2 (0.68) | PTGER2CA12CA1CA2CA4 | |
| SCHEMBL5046588 | 0.86 | PTGER2 (0.54) | PTGER2PTGER4 | |
| Hydrochloric Acid SCHEMBL5046674 | 0.85 | PTGER2 (0.65) | PTGER2CA12CA1CA2CA4 | |
| Hydrochloric Acid SCHEMBL5049406 | 0.85 | PTGER2 (0.72) | PTGER2CA12CA1CA2CA4 | |
| SCHEMBL5049443 | 0.84 | PTGER2 (0.79) | PTGER2CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442702-B2 | Treatment of bone disorders; carboxy derivatives | PFIZER INC. (US) | 2008-10-28 | — | — | US | disclosed |
| EP-1021410-B1 | PROSTAGLANDIN AGONISTS AND THEIR USE TO TREAT BONE DISORDERS | PFIZER (US) | 2006-12-27 | — | — | EP | disclosed |