Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 10/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | MMP14 | P50281 | 1/20 | 0.30 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.30 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | GPR183 | P32249 | 1/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3054403 | 0.93 | NR1H2 (0.36) | NR1H2POLBMAPTMMP1MMP9 | |
| SCHEMBL3042182 | 0.93 | NR1H2 (0.40) | NR1H2NR1H3 | |
| SCHEMBL3040914 | 0.92 | NR1H2 (0.38) | NR1H2NR1H3 | |
| SCHEMBL3034029 | 0.91 | NR1H2 (0.36) | P2RX7NR1H2ATRATRIP | |
| SCHEMBL3040414 | 0.91 | NR1H2 (0.34) | NR1H2NR1H3 | |
| SCHEMBL3046531 | 0.91 | SMN1; SMN2 (0.35) | P2RX7NR1H2NR1H3 | |
| SCHEMBL3044012 | 0.91 | NR1H2 (0.37) | NR1H2 | |
| SCHEMBL3039560 | 0.91 | NR1H2 (0.40) | NR1H2NR1H3 | |
| SCHEMBL3044144 | 0.89 | NR1H2 (0.33) | NR1H2NR1H3ATRATRIP | |
| SCHEMBL3045896 | 0.89 | MEN1 (0.34) | NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1880993-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-01-23 | — | — | EP | disclosed |