Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | CPT2 | P23786 | 1/20 | 0.37 |
| ▸ | CPT1A | P50416 | 1/20 | 0.37 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044141 | 0.86 | KLKB1 (0.48) | KLKB1KLK1CPT2CPT1ACPT1B | |
| SCHEMBL5039914 | 0.82 | CDC25A (0.45) | KLKB1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5039577 | 0.81 | KLKB1 (0.42) | KLKB1KLK1CPT2CPT1ACPT1B | |
| SCHEMBL5043868 | 0.79 | KLKB1 (0.46) | KLKB1KLK1CPT2CPT1ACPT1B | |
| SCHEMBL6069189 | 0.79 | KLKB1 (0.46) | KLKB1KLK1CPT2CPT1ACPT1B | |
| SCHEMBL5039559 | 0.79 | KLKB1 (0.46) | KLKB1KLK1CPT2CPT1ACPT1B | |
| SCHEMBL5045879 | 0.79 | KLKB1 (0.44) | KLKB1KLK1HDAC1HDAC8HDAC6 | |
| SCHEMBL5047187 | 0.78 | HDAC3 (0.36) | HDAC1HDAC6SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5048938 | 0.78 | KLKB1 (0.46) | KLKB1KLK1CPT2CPT1ACPT1B | |
| SCHEMBL5039321 | 0.78 | KLKB1 (0.45) | KLKB1KLK1CPT2CPT1ACPT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583762-B1 | PYRROLYL-THIAZOLES AND THEIR USE AS CB 1 RECEPTOR INVERSE AGONISTS | HOFFMANN LA ROCHE (CH) | 2008-07-09 | — | — | EP | claimed |