Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | SLC6A7 | Q99884 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3044082 | 0.91 | MEN1 (0.52) | LMNAKDRKDM4EMGLLSLC6A7 | |
| SCHEMBL3051090 | 0.88 | PARP1 (0.46) | LMNAKDRMGLLMEN1KMT2A | |
| SCHEMBL3034121 | 0.87 | KDR (0.48) | KDRMGLLAURKACDK1ALDH1A1 | |
| SCHEMBL3048935 | 0.87 | KDR (0.58) | KDRHPGDAURKACDK1ALDH1A1 | |
| SCHEMBL3047573 | 0.87 | KDR (0.46) | KDRMEN1KMT2AL3MBTL1HPGD | |
| SCHEMBL3044089 | 0.85 | KDR (0.45) | KDRMGLLHPGDAURKACDK1 | |
| SCHEMBL3043745 | 0.84 | KDR (0.47) | KDRMGLLMEN1KMT2AAURKA | |
| SCHEMBL3047646 | 0.84 | KDR (0.45) | KDRMGLLAURKACDK1 | |
| SCHEMBL3051432 | 0.84 | KDR (0.46) | KDRMGLLHPGDAURKACDK1 | |
| Hydrochloric Acid SCHEMBL3047329 | 0.83 | KDR (0.52) | KDRMGLLAURKACDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1880993-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-01-23 | — | — | EP | disclosed |