Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | TDO2 | P48775 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8111566 | 0.84 | RECQL (0.43) | LMNAMAPTMAPK1KMT2AIDO1 | |
| SCHEMBL6264184 | 0.80 | GAA (0.52) | LMNAMAPTHPGDKMT2AIDO1 | |
| Alcohol SCHEMBL10905551 | 0.80 | KMT2A (0.39) | LMNAMAPTHPGDCRHBPMAPK1 | |
| SCHEMBL31016250 | 0.79 | SMN1; SMN2 (0.42) | MAPTHPGDMAPK1KMT2AIDO1 | |
| SCHEMBL9567857 | 0.79 | SMN1; SMN2 (0.42) | MAPTHPGDMAPK1KMT2AIDO1 | |
| SCHEMBL11449400 | 0.79 | IDO1 (0.53) | LMNAMAPTMAPK1KMT2AIDO1 | |
| SCHEMBL31016248 | 0.79 | SMN1; SMN2 (0.42) | MAPTHPGDMAPK1KMT2AIDO1 | |
| SCHEMBL28043797 | 0.79 | CYP3A4 (0.45) | HPGDMAPK1KMT2AIDO1TDO2 | |
| SCHEMBL9644445 | 0.78 | HTR2A (0.43) | LMNAMAPTSMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL3833310 | 0.77 | CYP3A4 (0.43) | KMT2AIDO1TDO2SMN1; SMN2GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007741-A1 | ENANTIOMERICALLY PURE S-ETIFOXINE, PHARMACEUTICAL COMPOSITIONS THEREOF AND METHODS OF THEIR USE | Xytis Inc. (US) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007109288-A2 | ENANTIOMERICALLY PURE R-ETIFOXINE, PHARMACEUTICAL COMPOSITIONS THEREOF AND METHODS OF THEIR USE | XYTIS INC. (US) | 2007-09-27 | — | — | WO | disclosed |
| WO-2007109289-A1 | ENANTIOMERICALLY PURE S-ETIFOXINE, PHARMACEUTICAL COMPOSITIONS THEREOF AND METHODS OF THEIR USE | XYTIS INC. (US) | 2007-09-27 | — | — | WO | disclosed |