Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
| ▸ | PREP | P48147 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3605568 | 0.92 | DPP4 (0.58) | DPP4CTSKCTSSDPP8DPP9 | |
| SCHEMBL5696187 | 0.92 | DPP4 (0.58) | DPP4CTSKCTSSDPP8DPP9 | |
| SCHEMBL8301687 | 0.92 | DPP4 (0.58) | DPP4CTSKCTSSDPP8DPP9 | |
| SCHEMBL5053509 | 0.92 | DPP4 (0.58) | DPP4CTSKCTSSDPP8DPP9 | |
| SCHEMBL9003137 | 0.92 | DPP4 (0.58) | DPP4CTSKCTSSDPP8DPP9 | |
| SCHEMBL5696186 | 0.92 | DPP4 (0.58) | DPP4CTSKCTSSDPP8DPP9 | |
| SCHEMBL3604870 | 0.91 | POLB (0.48) | CTSKCTSSPOLBCTSLCTSB | |
| SCHEMBL5696171 | 0.91 | POLB (0.48) | CTSKCTSSPOLBCTSLCTSB | |
| SCHEMBL5696170 | 0.91 | POLB (0.48) | CTSKCTSSPOLBCTSLCTSB | |
| SCHEMBL27485070 | 0.91 | POLB (0.48) | CTSKCTSSPOLBCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919864-A2 | FAP INHIBITORS | Ferring B.V. (NL) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007085895-A2 | FAP INHIBITORS | FERRING B.V. (US) | 2007-08-02 | — | — | WO | disclosed |