Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 7/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 13/20 | 0.36 |
| ▸ | PDE4A | P27815 | 6/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.36 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL916480 | 1.00 | PDE4B (0.38) | PDE4BPDE4DPDE4APDE4CPROKR1 | |
| SCHEMBL916979 | 0.95 | PDE4B (0.39) | PDE4BPDE4DPDE4APDE4CPROKR1 | |
| SCHEMBL918227 | 0.95 | MEN1 (0.39) | PDE4BPDE4DPDE4APDE4CMEN1 | |
| SCHEMBL917232 | 0.93 | PDE4D (0.36) | PDE4BPDE4DPDE4APDE4CMEN1 | |
| SCHEMBL3676661 | 0.91 | PDE4D (0.37) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL3680467 | 0.91 | PDE4D (0.37) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL916681 | 0.89 | PIK3CD (0.39) | PDE4BPDE4DPDE4APDE4CPIK3CD | |
| SCHEMBL916770 | 0.89 | GRM5 (0.38) | PDE4BPDE4DPDE4APDE4CPROKR1 | |
| SCHEMBL917169 | 0.89 | PDE4D (0.38) | PDE4BPDE4DPDE4APDE4CMEN1 | |
| SCHEMBL918060 | 0.88 | PIK3CD (0.40) | PDE4BPDE4DPDE4APDE4CPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948167-A1 | COMPOSITIONS OF PHOSPHODIESTERASE TYPE IV INHIBITORS | RANBAXY LABORATORIES, LTD. (IN) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007045980-A1 | COMPOSITIONS OF PHOSPHODIESTERASE TYPE IV INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2007-04-26 | — | — | WO | disclosed |