Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 18/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3039557 | 0.90 | NR1H2 (0.40) | NR1H2NR1H3 | |
| SCHEMBL3037846 | 0.89 | NR1H2 (0.35) | NR1H2NR1H3JAK3BRD4CREBBP | |
| SCHEMBL3044795 | 0.88 | NR1H2 (0.35) | NR1H2NR1H3JAK3BRD4CREBBP | |
| SCHEMBL3045855 | 0.88 | NR1H2 (0.42) | NR1H2NR1H3BRD4CREBBP | |
| SCHEMBL3049636 | 0.86 | NR1H2 (0.32) | NR1H2NR1H3JAK3 | |
| SCHEMBL3047406 | 0.84 | NR1H2 (0.37) | NR1H2NR1H3 | |
| SCHEMBL3049642 | 0.84 | NR1H2 (0.37) | NR1H2NR1H3JAK3BRD4CREBBP | |
| SCHEMBL3048540 | 0.82 | NR1H2 (0.34) | NR1H2NR1H3 | |
| SCHEMBL3051211 | 0.82 | NR1H2 (0.35) | NR1H2NR1H3 | |
| SCHEMBL3037585 | 0.81 | NR1H2 (0.34) | NR1H2NR1H3BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1880993-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-01-23 | — | — | EP | disclosed |