Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1333093 | 0.88 | ADORA1 (0.45) | ADORA1TSHRADORA2BADORA2ALMNA | |
| SCHEMBL1334380 | 0.84 | ADORA1 (0.53) | ADORA1TSHRADORA2BADORA2ALMNA | |
| SCHEMBL4167641 | 0.81 | ADORA1 (0.52) | ADORA1TSHRADORA2BADORA2ALMNA | |
| Hydrochloric Acid SCHEMBL4174153 | 0.80 | ADORA1 (0.51) | ADORA1TSHRADORA2BADORA2ALMNA | |
| SCHEMBL1333068 | 0.80 | ADORA1 (0.48) | ADORA1TSHRADORA2BADORA2ALMNA | |
| SCHEMBL4182302 | 0.80 | ADORA1 (0.59) | ADORA1TSHRADORA2BADORA2ALMNA | |
| SCHEMBL1332421 | 0.78 | ADORA1 (0.40) | ADORA1TSHRADORA2BADORA2ALMNA | |
| SCHEMBL1333058 | 0.77 | ADORA1 (0.48) | ADORA1TSHRADORA2BADORA2ALMNA | |
| SCHEMBL1333442 | 0.77 | ADORA1 (0.46) | ADORA1TSHRADORA2BADORA2ALMNA | |
| SCHEMBL2073738 | 0.77 | ADORA1 (0.48) | ADORA1TSHRADORA2BADORA2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636229-A4 | A1 ADENOSINE RECEPTOR ANTOGONISTS | ENDACEA INC (US) | 2008-07-30 | — | — | EP | disclosed |
| EP-1636229-A2 | A1 ADENOSINE RECEPTOR ANTOGONISTS | Endacea, Inc. (US) | 2006-03-22 | — | — | EP | disclosed |
| WO-2005009343-A2 | A1 ADENOSINE RECEPTOR ANTOGONISTS | ENDACEA, INC. (US) | 2005-02-03 | — | — | WO | disclosed |