Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.39 |
| ▸ | FNTA | P49354 | 6/20 | 0.39 |
| ▸ | FNTB | P49356 | 6/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4947275 | 0.84 | TLR7 (0.52) | TLR7MEN1KMT2ANR1H2NR1H3 | |
| SCHEMBL5043352 | 0.84 | TLR7 (0.64) | TLR7MEN1KMT2AGAANR1H2 | |
| SCHEMBL6058798 | 0.75 | MEN1 (0.52) | TLR7MEN1KMT2ANR1H2NR1H3 | |
| SCHEMBL5046369 | 0.75 | CA12 (0.66) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL8211041 | 0.74 | CA12 (0.52) | MEN1KMT2ANR1H2NR1H3CA12 | |
| SCHEMBL13626587 | 0.74 | NR1H2 (0.43) | MEN1KMT2AGAANR1H2NR1H3 | |
| Hydrochloric Acid SCHEMBL5046437 | 0.74 | CA12 (0.51) | MEN1KMT2ANR1H2NR1H3CA12 | |
| SCHEMBL8272711 | 0.72 | PTGER2 (0.49) | MEN1KMT2ANR1H2NR1H3CA12 | |
| SCHEMBL1790266 | 0.72 | PPARA (0.57) | — | |
| SCHEMBL6466843 | 0.72 | PTGER2 (0.59) | NR1H2NR1H3FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442702-B2 | Treatment of bone disorders; carboxy derivatives | PFIZER INC. (US) | 2008-10-28 | — | — | US | disclosed |