Ethylene Glycol

Ethylene Glycol

SCHEMBL5050413

C=CC(=O)OCCCCCC.OCCO

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.75
HPGD P15428 1/20 0.75
ALDH1A1 P00352 3/20 0.70
CYP3A4 P08684 1/20 0.70
HCAR2 Q8TDS4 3/20 0.56
ATM Q13315 1/20 0.52
NAAA Q02083 1/20 0.50
TP53 P04637 2/20 0.48
HIF1A Q16665 2/20 0.48
HSD17B10 Q99714 1/20 0.48
EPHX1 P07099 1/20 0.47
ACHE P22303 3/20 0.45
THRB P10828 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL10954362 1.00 TSHR (0.75) TSHRHPGDALDH1A1CYP3A4HCAR2
Ethylene Glycol SCHEMBL5050410 0.98 TSHR (0.72) TSHRHPGDALDH1A1CYP3A4HCAR2
Myristyl Alcohol SCHEMBL5499831 0.95 TSHR (0.72) TSHRHPGDALDH1A1CYP3A4HCAR2
1,6-Hexanediol SCHEMBL22389547 0.95 TSHR (0.72) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL6677892 0.95 TSHR (0.72) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL6685941 0.95 TSHR (0.72) TSHRHPGDALDH1A1CYP3A4HCAR2
Butyl Alcohol SCHEMBL10954715 0.95 TSHR (0.72) TSHRHPGDALDH1A1CYP3A4HCAR2
Nonanol SCHEMBL21638808 0.95 TSHR (0.72) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL6686694 0.95 TSHR (0.72) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL6689995 0.95 TSHR (0.72) TSHRHPGDALDH1A1CYP3A4HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1915888-A2 METHOD AND COMPOSITION FOR ADHERING MATERIALS TOGETHER MOLECULAR IMPRINTS, INC. (US) 2008-04-30 EP disclosed
WO-2007050133-A2 METHOD AND COMPOSITION FOR ADHERING MATERIALS TOGETHER MOLECULAR IMPRINTS, INC. (US) 2007-05-03 WO disclosed
EP-0130804-B1 PHOTOSENSITIVE RESIN COMPOSITION KOGYO GIJUTSUIN (JP) 1989-02-08 EP disclosed
US-4564580-A SAPONIFIED VINYL ACETATE POLYMER REACTED WITH STRYLPYRIDINIUM OR S KOGYO GIJUTSUIN (JP) 1986-01-14 US disclosed
EP-0130804-A2 Photosensitive resin composition KOGYO GIJUTSUIN (JP) 1985-01-09 EP disclosed