Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | MST1R | Q04912 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 4/20 | 0.37 |
| ▸ | BCR | P11274 | 4/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3034098 | 0.88 | CRBN (0.41) | GBA1CNR2CRBNMEN1KMT2A | |
| SCHEMBL3039265 | 0.87 | MEN1 (0.41) | GPR119CNR2CRBNMEN1KMT2A | |
| SCHEMBL3041591 | 0.87 | MEN1 (0.43) | GPR119CNR2CRBNMEN1KMT2A | |
| SCHEMBL3050148 | 0.86 | CFTR (0.39) | GPR119CNR2CRBNMEN1KMT2A | |
| SCHEMBL3044424 | 0.86 | CACNA1B (0.39) | GPR119CNR2CRBNMEN1KMT2A | |
| SCHEMBL3151651 | 0.84 | MEN1 (0.36) | GPR119CNR2CRBNMEN1KMT2A | |
| SCHEMBL3046089 | 0.84 | CCNA2 (0.40) | CNR2CRBNMEN1KMT2ANR1H2 | |
| SCHEMBL3047862 | 0.83 | GBA1 (0.39) | GBA1GPR119CNR2ABL1BCR | |
| SCHEMBL3048669 | 0.82 | LTK (0.36) | LTKCDK5MST1RDYRK1ACLK4 | |
| SCHEMBL3033984 | 0.80 | MEN1 (0.43) | GPR119CNR2CRBNMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1880993-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-01-23 | — | — | EP | disclosed |