Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665338 | 0.95 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4CA2 | |
| SCHEMBL27856672 | 0.90 | TSHR (0.52) | TSHRHPGDALDH1A1CYP3A4CA2 | |
| SCHEMBL27646662 | 0.87 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4CA2 | |
| 2-Ethylhexanoic Acid SCHEMBL27664726 | 0.85 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4CA2 | |
| SCHEMBL29448450 | 0.84 | TSHR (0.64) | TSHRHPGDALDH1A1CYP3A4CA2 | |
| SCHEMBL19133682 | 0.83 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4MAPK1 | |
| SCHEMBL27887847 | 0.83 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4CA2 | |
| SCHEMBL15315064 | 0.82 | TSHR (0.52) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL28108439 | 0.82 | TSHR (0.52) | TSHRHPGDALDH1A1CYP3A4MAPK1 | |
| SCHEMBL7647314 | 0.81 | TSHR (0.65) | TSHRHPGDALDH1A1CYP3A4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080281014-A1 | Nanosubstance-Containing Composition, Process for Producing the Same, and Composite Made With the Same | MITSUBISHI RAYON CO., LTD. (JP) | 2008-11-13 | — | — | US | disclosed |