Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27428629 | 0.90 | TSHR (0.51) | TSHRHPGDRECQLALDH1A1CYP3A4 | |
| SCHEMBL5057275 | 0.83 | TSHR (0.53) | TSHRHPGDRECQLALDH1A1CYP3A4 | |
| SCHEMBL10601327 | 0.81 | HCAR2 (0.45) | TSHRRECQLTP53ATMTDP1 | |
| SCHEMBL169554 | 0.80 | TSHR (0.57) | TSHRHPGDRECQLALDH1A1CYP3A4 | |
| SCHEMBL6049057 | 0.79 | TSHR (0.52) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL19456761 | 0.78 | TSHR (0.87) | TSHRHPGDRECQLALDH1A1CYP3A4 | |
| SCHEMBL1480795 | 0.78 | TSHR (0.87) | TSHRHPGDRECQLALDH1A1CYP3A4 | |
| SCHEMBL5057261 | 0.78 | TSHR (0.47) | TSHRRECQLALDH1A1CYP3A4TP53 | |
| SCHEMBL28788191 | 0.78 | TSHR (0.54) | TSHRHPGDRECQLALDH1A1CYP3A4 | |
| SCHEMBL6049061 | 0.77 | TSHR (0.48) | TSHRHPGDALDH1A1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080281014-A1 | Nanosubstance-Containing Composition, Process for Producing the Same, and Composite Made With the Same | MITSUBISHI RAYON CO., LTD. (JP) | 2008-11-13 | — | — | US | disclosed |