Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 11/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | FAP | Q12884 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5051649 | 1.00 | DPP4 (1.00) | DPP4KCNH2CHRM1FAP | |
| Hydrochloric Acid SCHEMBL4220122 | 0.99 | DPP4 (0.99) | DPP4KCNH2CHRM1FAP | |
| Hydrochloric Acid SCHEMBL4220124 | 0.99 | DPP4 (0.99) | DPP4KCNH2CHRM1FAP | |
| SCHEMBL8237500 | 0.92 | DPP4 (0.88) | DPP4KCNH2CHRM1FAP | |
| SCHEMBL4230403 | 0.91 | DPP4 (1.00) | DPP4KCNH2CHRM1FAP | |
| SCHEMBL4230400 | 0.91 | DPP4 (1.00) | DPP4KCNH2CHRM1FAP | |
| SCHEMBL12047552 | 0.88 | DPP4 (0.79) | DPP4KCNH2FAP | |
| SCHEMBL4225476 | 0.88 | DPP4 (1.00) | DPP4KCNH2CHRM1FAP | |
| SCHEMBL4225482 | 0.88 | DPP4 (1.00) | DPP4KCNH2CHRM1FAP | |
| SCHEMBL12047551 | 0.86 | DPP4 (0.76) | DPP4KCNH2CHRM1FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966215-A1 | CONDENSED HETEROCYCLIC COMPOUNDS USEFUL AS DPP-IV INHIBITORS | Novartis AG (CH) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007071738-A1 | CONDENSED HETEROCYCLIC COMPOUNDS USEFUL AS DPP-IV INHIBITORS | NOVARTIS AG (CH) | 2007-06-28 | — | — | WO | disclosed |