Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 13/20 | 0.46 |
| ▸ | CDK2 | P24941 | 13/20 | 0.46 |
| ▸ | CCND1 | P24385 | 10/20 | 0.46 |
| ▸ | CDK6 | Q00534 | 10/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3679034 | 1.00 | MAPK14 (0.50) | MAPK14LCKMAPK8MAPK9MAPK10 | |
| SCHEMBL917150 | 0.95 | MAPK14 (0.53) | MAPK14LCKMAPK8MAPK9MAPK10 | |
| SCHEMBL3679319 | 0.94 | MAPK14 (0.51) | MAPK14LCKMAPK8MAPK9MAPK10 | |
| SCHEMBL3669720 | 0.93 | MAPK14 (0.51) | MAPK14LCKMAPK8MAPK9MAPK10 | |
| SCHEMBL3670892 | 0.92 | MAPK14 (0.48) | MAPK14LCKMAPK8MAPK9MAPK10 | |
| SCHEMBL3674660 | 0.92 | MAPK14 (0.50) | MAPK14LCKMAPK8MAPK9MAPK10 | |
| SCHEMBL3677712 | 0.92 | MAPK14 (0.52) | MAPK14LCKMAPK8MAPK9MAPK10 | |
| SCHEMBL3672038 | 0.91 | MAPK14 (0.50) | MAPK14LCKMAPK8MAPK9MAPK10 | |
| SCHEMBL3672961 | 0.91 | MAPK14 (0.50) | MAPK14LCKMAPK8MAPK9MAPK10 | |
| SCHEMBL3576254 | 0.90 | MAPK14 (0.53) | MAPK14LCKMAPK8MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948167-A1 | COMPOSITIONS OF PHOSPHODIESTERASE TYPE IV INHIBITORS | RANBAXY LABORATORIES, LTD. (IN) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007045980-A1 | COMPOSITIONS OF PHOSPHODIESTERASE TYPE IV INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2007-04-26 | — | — | WO | disclosed |