Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12266699 | 0.92 | TSHR (0.46) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL26254168 | 0.91 | MEN1 (0.32) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL15610025 | 0.90 | MEN1 (0.45) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL16169878 | 0.90 | MEN1 (0.45) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL15610479 | 0.90 | MEN1 (0.45) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL17916203 | 0.90 | MEN1 (0.45) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL15609723 | 0.90 | MEN1 (0.45) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL16169882 | 0.90 | MEN1 (0.45) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL10301164 | 0.90 | MEN1 (0.45) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL13330243 | 0.89 | MEN1 (0.32) | TSHRMEN1THRBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7268176-B2 | Additives for imparting mar and scratch resistance and compositions comprising the same | PPG INDUSTRIES OHIO, INC. (US) | 2007-09-11 | — | — | US | claimed |
| US-6835458-B2 | Additive fromulation: reaction product of carbinol functional siloxane surfactant and a carboxylic acid containing compound, particles selected from silica, alumina, borosilicate glass, quartz and zircon dispersed in siloxane | PPG INDUSTRIES OHIO, INC. | 2004-12-28 | — | — | US | claimed |
| US-20040209088-A1 | COATING COMPOSITION HAVING IMPROVED MAR AND SCRATCH PROPERTIES | PPG INDUSTRIES OHIO, INC. | 2004-10-21 | — | — | US | claimed |
| US-20040116585-A1 | Novel additives for imparting mar and scratch resistance and compositions comprising the same | PPG INDUSTRIES OHIO, INC. | 2004-06-17 | — | — | US | claimed |
| US-8734821-B2 | Silicone surfactant-based agricultural formulations and methods for the use thereof | OMS INVESTMENTS, INC. (US) | 2014-05-27 | — | — | US | disclosed |
| US-20080221223-A1 | Nonionic surfactant comprising 2,5,8,11-tetramethyl-6-dodecyn-5,8-diol ethoxylate; ethoxylated-2,4,7,9-tetramethyl 5 decyn-4,7-diol; alkylpyrrolidones; polyether modified polysiloxane or trisiloxane ethoxylate; rapid knockdown of cockroaches | OMS INVESTMENTS INC. (US) | 2008-09-11 | — | — | US | disclosed |
| US-7345108-B2 | Additives for imparting mar and scratch resistance and compositions comprising the same | PPG INDUSTRIES OHIO, INC. (US) | 2008-03-18 | — | — | US | disclosed |
| US-20070266750-A1 | Silicone surfactant-based agricultural formulations and methods for the use thereof | JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT | 2007-11-22 | — | — | US | disclosed |
| US-20070266749-A1 | Pesticidal compositions for treating anthropods and methods for the use thereof | OMS INVESTMENTS, INC. | 2007-11-22 | — | — | US | disclosed |
| US-7268176-B2 | Additives for imparting mar and scratch resistance and compositions comprising the same | PPG INDUSTRIES OHIO, INC. (US) | 2007-09-11 | — | — | US | disclosed |
| US-20060078748-A1 | Novel additives for imparting Mar and scratch resistance and compositions comprising the same | AMBROSE RONALD R | 2006-04-13 | — | — | US | disclosed |
| US-6835458-B2 | Additive fromulation: reaction product of carbinol functional siloxane surfactant and a carboxylic acid containing compound, particles selected from silica, alumina, borosilicate glass, quartz and zircon dispersed in siloxane | PPG INDUSTRIES OHIO, INC. | 2004-12-28 | — | — | US | disclosed |
| US-20040209088-A1 | COATING COMPOSITION HAVING IMPROVED MAR AND SCRATCH PROPERTIES | PPG INDUSTRIES OHIO, INC. | 2004-10-21 | — | — | US | disclosed |
| US-20040116585-A1 | Novel additives for imparting mar and scratch resistance and compositions comprising the same | PPG INDUSTRIES OHIO, INC. | 2004-06-17 | — | — | US | disclosed |
| EP-0933376-B1 | Silanyl-triazines as light screening compositions | HOFFMANN LA ROCHE (CH) | 2003-08-20 | — | — | EP | disclosed |
| US-6018044-A | TRIS((ALKYL, SILANE, OLIGOSILOXANE OR POLYSILOXANE)(OXY OR AMINO)CARBONYL-(1,4-PHENYLENE)-AMINO)-S-TRIAZINES HAVING AT LEAST ONE SILICON CONTAINING MOIETY OF GIVEN FORMULA; USE AS UV-B FILTERS IN LIGHT SCREENING COMPOSITIONS | ROCHE VITAMINS INC. (US) | 2000-01-25 | — | — | US | disclosed |
| EP-0933376-A2 | Silanyl-triazines as light screening compositions | F. HOFFMANN-LA ROCHE AG (CH) | 1999-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221223-A1 | Nonionic surfactant comprising 2,5,8,11-tetramethyl-6-dodecyn-5,8-diol ethoxylate; ethoxylated-2,4,7,9-tetramethyl 5 decyn-4,7-diol; alkylpyrrolidones; polyether modified polysiloxane or trisiloxane ethoxylate; rapid knockdown of cockroaches | LNPK, OR10J3, SRRT | TSHR 2250/4885MEN1 4133/4885THRB 1955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.