Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 6/20 | 0.39 |
| ▸ | RAF1 | P04049 | 5/20 | 0.39 |
| ▸ | KDR | P35968 | 5/20 | 0.39 |
| ▸ | KRAS | P01116 | 4/20 | 0.39 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 3/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | CCNC | P24863 | 2/20 | 0.33 |
| ▸ | CDK8 | P49336 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5061791 | 0.91 | CYP1A2 (0.39) | BRAFRAF1KDRKRASMAP2K2 | |
| SCHEMBL4419440 | 0.89 | BRAF (0.48) | BRAFRAF1KDRKRASMAP2K2 | |
| SCHEMBL5054892 | 0.86 | HTR2B (0.39) | BRAFRAF1KDRCYP1A2CYP3A4 | |
| SCHEMBL4274689 | 0.76 | BRAF (0.49) | BRAFRAF1KDRKRASMAP2K2 | |
| SCHEMBL4275692 | 0.75 | BRAF (0.49) | BRAFRAF1KDRKRASMAP2K2 | |
| SCHEMBL5054692 | 0.75 | BRAF (0.47) | BRAFRAF1KDRKRASMAP2K2 | |
| SCHEMBL5060173 | 0.75 | BRAF (0.47) | BRAFRAF1KDRKRASMAP2K2 | |
| SCHEMBL5056343 | 0.75 | BRAF (0.47) | BRAFRAF1KDRKRASMAP2K2 | |
| SCHEMBL5062456 | 0.74 | BRAF (0.47) | BRAFRAF1KDRKRASMAP2K2 | |
| SCHEMBL5059965 | 0.74 | BRAF (0.46) | BRAFRAF1KDRKRASCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113967-A1 | ENZYME MODULATORS AND TREATMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2008-05-15 | — | — | US | claimed |
| EP-1947076-B1 | PROCESS FOR PRODUCING AROMATIC COMPOUNDS | IDEMITSU KOSAN CO (JP) | 2014-08-13 | — | — | EP | disclosed |
| EP-1947076-A1 | PROCESS FOR PRODUCING AROMATIC COMPOUND AND AROMATIC COMPOUND OBTAINED BY THE PROCESS | Idemitsu Kosan Co., Ltd. (JP) | 2008-07-23 | — | — | EP | disclosed |
| EP-1659129-A1 | COORDINATION METAL COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, MATERIAL FOR LUMINESCENT COATING FORMATION AND ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2006-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113967-A1 | ENZYME MODULATORS AND TREATMENTS | ABL2, BRAF, MAP3K1 | BRAF 2/4885RAF1 55/4885KDR 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.