Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 14/20 | 0.39 |
| ▸ | RAF1 | P04049 | 4/20 | 0.39 |
| ▸ | BRAF | P15056 | 7/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5054927 | 0.91 | MAPK14 (0.45) | KDRRAF1BRAFMAPK14MAPK13 | |
| SCHEMBL5052098 | 0.90 | KDR (0.37) | KDRRAF1BRAFMAPK14TEK | |
| SCHEMBL5055055 | 0.89 | KDR (0.40) | KDRRAF1BRAFAURKAAURKB | |
| SCHEMBL5052150 | 0.88 | KDR (0.40) | KDRRAF1BRAFAURKAAURKB | |
| SCHEMBL5055128 | 0.87 | KDR (0.38) | KDRRAF1BRAFAURKAAURKB | |
| SCHEMBL5055018 | 0.86 | ABL1 (0.45) | KDRRAF1BRAFAURKAAURKB | |
| SCHEMBL5055357 | 0.86 | ABL1 (0.47) | KDRRAF1BRAFAURKAAURKB | |
| SCHEMBL5059949 | 0.86 | RAF1 (0.53) | KDRRAF1BRAFAURKAAURKB | |
| SCHEMBL5055114 | 0.86 | FLT3 (0.41) | KDRBRAFMAPK14MAPK13 | |
| SCHEMBL5054943 | 0.84 | KDR (0.44) | KDRRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113967-A1 | ENZYME MODULATORS AND TREATMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2008-05-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113967-A1 | ENZYME MODULATORS AND TREATMENTS | ABL2, BRAF, MAP3K1 | KDR 41/4885RAF1 55/4885BRAF 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.