Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 4/20 | 0.60 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.51 |
| ▸ | BRAF | P15056 | 12/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | AXL | P30530 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 2/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2030984 | 0.91 | ABL1 (0.74) | ABL1MAPK13BRAFKDRMAPK14 | |
| SCHEMBL30681075 | 0.91 | ABL1 (0.74) | ABL1MAPK13BRAFKDRMAPK14 | |
| SCHEMBL5055047 | 0.90 | ABL1 (0.61) | ABL1MAPK13BRAFMAPK14AXL | |
| SCHEMBL5062414 | 0.90 | KDR (0.50) | ABL1BRAFKDRMAPK14AXL | |
| SCHEMBL5055131 | 0.89 | MAPK13 (0.52) | ABL1MAPK13BRAFKDRMAPK14 | |
| SCHEMBL5052217 | 0.88 | MAPK13 (0.53) | ABL1MAPK13BRAFKDRMAPK14 | |
| SCHEMBL5052164 | 0.85 | BRAF (0.61) | ABL1MAPK13BRAFKDRMAPK14 | |
| SCHEMBL5055115 | 0.85 | ABL1 (0.64) | ABL1MAPK13BRAFMAPK14AXL | |
| SCHEMBL5052111 | 0.85 | MAPK13 (0.57) | ABL1MAPK13BRAFKDRMAPK14 | |
| SCHEMBL2081834 | 0.84 | ABL1 (0.82) | ABL1MAPK13BRAFKDRMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113967-A1 | ENZYME MODULATORS AND TREATMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2008-05-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113967-A1 | ENZYME MODULATORS AND TREATMENTS | ABL2, BRAF, MAP3K1 | ABL1 20/4885MAPK13 118/4885BRAF 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.