Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 6/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 5/20 | 0.45 |
| ▸ | KDR | P35968 | 5/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.45 |
| ▸ | MET | P08581 | 4/20 | 0.45 |
| ▸ | FLT3 | P36888 | 3/20 | 0.45 |
| ▸ | BRAF | P15056 | 2/20 | 0.45 |
| ▸ | ABL1 | P00519 | 2/20 | 0.45 |
| ▸ | PLK4 | O00444 | 1/20 | 0.45 |
| ▸ | ACOX3 | O15254 | 1/20 | 0.45 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.45 |
| ▸ | STK10 | O94804 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | RAF1 | P04049 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5052243 | 0.91 | AXL (0.51) | AXLMAPK14MAPK13CSF1RKDR | |
| SCHEMBL5054647 | 0.91 | KDR (0.53) | AXLMAPK14MAPK13CSF1RKDR | |
| SCHEMBL5062761 | 0.90 | MAPK14 (0.61) | AXLMAPK14MAPK13CSF1RKDR | |
| SCHEMBL5059997 | 0.90 | AXL (0.62) | AXLMAPK14MAPK13CSF1RKDR | |
| SCHEMBL30681098 | 0.89 | AXL (0.58) | AXLMAPK14CSF1RKDRPDGFRA | |
| SCHEMBL2030655 | 0.89 | AXL (0.58) | AXLMAPK14CSF1RKDRPDGFRA | |
| SCHEMBL5056525 | 0.88 | MAPK14 (0.48) | AXLMAPK14MAPK13CSF1RKDR | |
| SCHEMBL2926980 | 0.88 | MAPK14 (0.58) | AXLMAPK14CSF1RKDRPDGFRA | |
| SCHEMBL2918935 | 0.87 | AXL (0.52) | AXLMAPK14MAPK13CSF1RKDR | |
| SCHEMBL573542 | 0.87 | AXL (0.57) | AXLMAPK14MAPK13CSF1RKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113967-A1 | ENZYME MODULATORS AND TREATMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2008-05-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113967-A1 | ENZYME MODULATORS AND TREATMENTS | ABL2, BRAF, MAP3K1 | AXL 117/4885MAPK14 100/4885MAPK13 118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.