Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 5/20 | 0.47 |
| ▸ | CSF1R | P07333 | 14/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 9/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.44 |
| ▸ | FLT3 | P36888 | 5/20 | 0.44 |
| ▸ | MET | P08581 | 5/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | WNT1 | P04628 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | CLK3 | P49761 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5062413 | 0.91 | KDR (0.55) | AXLKDRCSF1RPDGFRAPDGFRB | |
| SCHEMBL5054893 | 0.91 | AXL (0.46) | AXLKDRCSF1RPDGFRAPDGFRB | |
| SCHEMBL5052264 | 0.90 | AXL (0.55) | AXLKDRCSF1RPDGFRAPDGFRB | |
| SCHEMBL5054948 | 0.89 | AXL (0.52) | AXLKDRCSF1RPDGFRAPDGFRB | |
| SCHEMBL5059980 | 0.89 | CSF1R (0.47) | AXLKDRCSF1RPDGFRAPDGFRB | |
| SCHEMBL5059922 | 0.89 | KDR (0.41) | KDRMAPK13MAPK14ABL1 | |
| SCHEMBL5052211 | 0.88 | AXL (0.50) | AXLKDRCSF1RPDGFRAPDGFRB | |
| SCHEMBL5056710 | 0.86 | AXL (0.47) | AXLKDRCSF1RPDGFRAPDGFRB | |
| SCHEMBL5062798 | 0.86 | AXL (0.47) | AXLKDRCSF1RPDGFRAPDGFRB | |
| SCHEMBL5060540 | 0.85 | MAPK14 (0.57) | KDRMAPK13MAPK14ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113967-A1 | ENZYME MODULATORS AND TREATMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2008-05-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113967-A1 | ENZYME MODULATORS AND TREATMENTS | ABL2, BRAF, MAP3K1 | AXL 117/4885KDR 41/4885CSF1R 979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.