Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.44 |
| ▸ | BRAF | P15056 | 10/20 | 0.41 |
| ▸ | KDR | P35968 | 9/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5062347 | 0.91 | KDR (0.39) | MAPK14MAPK13BRAFKDRNPC1 | |
| SCHEMBL5054952 | 0.91 | MAPK14 (0.56) | MAPK14MAPK13BRAFKDR | |
| SCHEMBL5055128 | 0.91 | KDR (0.38) | MAPK14MAPK13BRAFKDRNPC1 | |
| SCHEMBL5055012 | 0.89 | MAPK14 (0.44) | MAPK14MAPK13BRAFKDRNPC1 | |
| SCHEMBL5062440 | 0.87 | RAF1 (0.51) | MAPK14MAPK13BRAFKDRLCK | |
| SCHEMBL5054927 | 0.87 | MAPK14 (0.45) | MAPK14MAPK13BRAFKDRLCK | |
| SCHEMBL5052253 | 0.85 | MAPK14 (0.44) | MAPK14MAPK13BRAFKDRLCK | |
| SCHEMBL5060550 | 0.85 | MAPK14 (0.44) | MAPK14MAPK13BRAFKDRLCK | |
| SCHEMBL5054999 | 0.85 | KDR (0.43) | KDRNPC1RAB9ASMN1; SMN2FLT1 | |
| SCHEMBL5056645 | 0.84 | ABL1 (0.49) | MAPK14MAPK13BRAFKDRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113967-A1 | ENZYME MODULATORS AND TREATMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2008-05-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113967-A1 | ENZYME MODULATORS AND TREATMENTS | ABL2, BRAF, MAP3K1 | MAPK14 100/4885MAPK13 118/4885BRAF 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.