⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5058853 | 0.81 | — | — | |
| SCHEMBL20160138 | 0.74 | — | — | |
| SCHEMBL20237126 | 0.73 | — | — | |
| SCHEMBL31392761 | 0.69 | — | — | |
| SCHEMBL5055404 | 0.67 | — | — | |
| SCHEMBL18699362 | 0.67 | — | — | |
| Ethylenediamine SCHEMBL11023353 | 0.63 | — | — | |
| Ethylenediamine SCHEMBL9190307 | 0.63 | — | — | |
| SCHEMBL12239875 | 0.62 | — | — | |
| SCHEMBL3439517 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004083365-A9 | COMPOUNDS AND THEIR USE FOR SPECIFIC AND SIMULTANEOUS INHIBITION OF GENES INVOLVED IN DISEASES AND RELATED DRUGS | INST NAT SANTE RECH MED (FR) | 2008-07-10 | — | — | WO | claimed |
| US-20080108581-A1 | Compounds and Their Use for Specific and Simultaneous Inhibition of Genes Involved In Diseases and Related Drugs | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (I.N.S.E.R.M.) (FR) | 2008-05-08 | — | — | US | claimed |
| JP-2006523646-A | — | — | 2006-10-19 | — | — | JP | claimed |
| EP-1606405-A2 | COMPOUNDS AND THEIR USE FOR SPECIFIC AND SIMULTANEOUS INHIBITION OF GENES INVOLVED IN DISEASES AND RELATED DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2005-12-21 | — | — | EP | claimed |
| WO-2004083365-A2 | COMPOUNDS AND THEIR USE FOR SPECIFIC AND SIMULTANEOUS INHIBITION OF GENES INVOLVED IN DISEASES AND RELATED DRUGS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2004-09-30 | — | — | WO | claimed |
| CN-102869660-A | Aminothiazolones as estrogen related receptor-alpha modulators | JANSSEN PHARMACEUTICA NV | 2013-01-09 | — | — | CN | disclosed |
| CN-102834392-A | Aminothiazolones as estrogen related receptor-alpha modulators | JANSSEN PHARMACEUTICA NV | 2012-12-19 | — | — | CN | disclosed |
| CN-101679326-B | Substituted phenoxy n-alkylated thiazoledinedione as estrogen related receptor-alpha modulators | JANSSEN PHARMACEUTICA NV | 2012-12-12 | — | — | CN | disclosed |
| CN-102770429-A | Substituted aminothiazolone indazoles as estrogen related receptor-alpha modulators | JANSSEN PHARMACEUTICA NV | 2012-11-07 | — | — | CN | disclosed |
| CN-101355876-B | Composition suitable for ophthalmic administration | COMBINATORX INC | 2012-09-05 | — | — | CN | disclosed |
| CN-101679326-A | Substituted phenoxy n-alkylated thiazoledinedione as estrogen related receptor-alpha modulators | JANSSEN PHARMACEUTICA NV | 2010-03-24 | — | — | CN | disclosed |
| CN-101679322-A | Substituted phenoxy thiazolidinediones as estrogen related receptor-alpha modulators | JANSSEN PHARMACEUTICA NV | 2010-03-24 | — | — | CN | disclosed |
| CN-101355876-A | Methods, compositions and kits for treating medical conditions | COMBINATORX INC (US) | 2009-01-28 | — | — | CN | disclosed |
| CN-101102760-A | Methods and agents for treating immunoinflammatory disorders | COMBINATORX (US) | 2008-01-09 | — | — | CN | disclosed |
| CN-100355714-C | Arylpiperazines having 5-hydroxyl-typtamine activity | LILLY CO ELI (US) | 2007-12-19 | — | — | CN | disclosed |
| CN-1889956-A | Methods and reagents for the treatment of immunoinflammatory disorders | COMBINATORX INC (US) | 2007-01-03 | — | — | CN | disclosed |
| CN-1761478-A | Combination therapy for the treatment of immunoinflammatory disorders | COMBINATORX INC (US) | 2006-04-19 | — | — | CN | disclosed |
| CN-1743302-A | Arylpiperazines having 5-hydroxyl-typtamine activity | LILLY CO ELI (US) | 2006-03-08 | — | — | CN | disclosed |
| CN-1227241-C | Having 5-hydroxytryptamine 1AReceptor-active arylpiperazines | LILLY CO ELI (US) | 2005-11-16 | — | — | CN | disclosed |
| CN-1290258-A | Aryl piperazine compounds with 5-hydroxytryptamine 1A receptor activity | LILLY CO ELI (US) | 2001-04-04 | — | — | CN | disclosed |