⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12449218 | 1.00 | — | — | |
| SCHEMBL10427350 | 1.00 | — | — | |
| SCHEMBL10310643 | 1.00 | — | — | |
| SCHEMBL10427351 | 1.00 | — | — | |
| SCHEMBL51211 | 1.00 | — | — | |
| SCHEMBL5055917 | 1.00 | — | — | |
| Methyl Alcohol SCHEMBL27790667 | 0.95 | GLA (0.35) | — | |
| Alcohol SCHEMBL27811862 | 0.92 | GLA (0.38) | — | |
| SCHEMBL5573446 | 0.92 | — | — | |
| SCHEMBL163320 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759395-B2 | Di- and tri-hydroxy derivatives of eicosapentaenoic acid and docosahexaenoic acid coadministered with a cyclooxygenase-2 inhibitor; antiinflammatory agents | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2010-07-20 | — | — | US | disclosed |
| US-20080199912-A1 | Methods for Obtaining Optically Active Epoxides and Diols from 2,3-Disubstituted and 2,3-Trisubstituted Epoxides | OXYRANE (UK) LTD. (GB) | 2008-08-21 | — | — | US | disclosed |
| EP-1896597-A2 | METHODS FOR OBTAINING OPTICALLY ACTIVE EPOXIDES AND DIOLS FROM 2,3-DISUBSTITUTED AND 2,3-TRISUBSTITUTED EPOXIDES | CSIR (ZA) | 2008-03-12 | — | — | EP | disclosed |
| WO-2007069079-A2 | METHODS FOR OBTAINING OPTICALLY ACTIVE EPOXIDES AND DIOLS FROM 2,3-DISUBSTITUTED AND 2,3-TRISUBSTITUTED EPOXIDES | CSIR (US) | 2007-06-21 | — | — | WO | disclosed |
| US-6979733-B2 | Epoxide hydrolases, nucleic acids encoding them and methods of making and using them | DIVERSA CORPORATION (US) | 2005-12-27 | — | — | US | disclosed |
| EP-1578987-A2 | EPOXIDE HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | Diversa Corporation (US) | 2005-09-28 | — | — | EP | disclosed |
| US-6943001-B2 | Epoxide hydrolases, nucleic acids encoding them and methods for making and using them | DIVERSA CORPORATION (US) | 2005-09-13 | — | — | US | disclosed |
| WO-2004090101-A2 | EPOXIDE HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | DIVERSA CORPORATION (US) | 2004-10-21 | — | — | WO | disclosed |
| US-20030148443-A1 | Epoxide hydrolases, nucleic acids encoding them and methods of making and using them | VERENIUM CORPORATION | 2003-08-07 | — | — | US | disclosed |
| US-20030148490-A1 | Epoxide hydrolases, nucleic acids encoding them and methods for making and using them | VERENIUM CORPORATION | 2003-08-07 | — | — | US | disclosed |
| WO-2003012126-A2 | EPOXIDE HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | DIVERSA CORPORATION (US) | 2003-02-13 | — | — | WO | disclosed |