Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 4/20 | 0.63 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.54 |
| ▸ | BRAF | P15056 | 12/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.54 |
| ▸ | AXL | P30530 | 1/20 | 0.53 |
| ▸ | SRC | P12931 | 2/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5055115 | 0.91 | ABL1 (0.64) | ABL1MAPK13BRAFMAPK14AXL | |
| SCHEMBL5054898 | 0.91 | ABL1 (0.53) | ABL1MAPK13BRAFMAPK14AXL | |
| SCHEMBL5062076 | 0.90 | ABL1 (0.77) | ABL1MAPK13BRAFMAPK14AXL | |
| SCHEMBL5062187 | 0.90 | ABL1 (0.62) | ABL1MAPK13BRAFMAPK14AXL | |
| SCHEMBL5062157 | 0.87 | MAPK13 (0.54) | ABL1MAPK13BRAFMAPK14AXL | |
| SCHEMBL2081834 | 0.86 | ABL1 (0.82) | ABL1MAPK13BRAFMAPK14AXL | |
| SCHEMBL5052187 | 0.86 | MAPK13 (0.55) | ABL1MAPK13BRAFMAPK14AXL | |
| SCHEMBL2083762 | 0.86 | ABL1 (0.61) | ABL1MAPK13BRAFMAPK14AXL | |
| SCHEMBL5055047 | 0.84 | ABL1 (0.61) | ABL1MAPK13BRAFMAPK14AXL | |
| SCHEMBL16327294 | 0.84 | ABL1 (0.78) | ABL1MAPK13BRAFMAPK14AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113967-A1 | ENZYME MODULATORS AND TREATMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2008-05-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113967-A1 | ENZYME MODULATORS AND TREATMENTS | ABL2, BRAF, MAP3K1 | ABL1 20/4885MAPK13 118/4885BRAF 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.