SCHEMBL5057804

SCHEMBL5057804

C=CCCCCCCCCCCCCCC[Si](Cl)(Cl)Cl

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
ABCC4 O15439 1/20 0.39
MAPT P10636 1/20 0.39
ALDH1A1 P00352 4/20 0.38
TRPA1 O75762 3/20 0.37
LPAR3 Q9UBY5 2/20 0.34
LMNA P02545 2/20 0.34
LPAR2 Q9HBW0 1/20 0.34
TDP1 Q9NUW8 2/20 0.34
USP2 O75604 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3688333 1.00 TSHR (0.46) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL6037342 1.00 TSHR (0.46) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL6037325 1.00 TSHR (0.46) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL9245840 1.00 TSHR (0.46) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL388270 1.00 TSHR (0.46) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL3886937 1.00 TSHR (0.46) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL3449829 1.00 TSHR (0.46) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL5051955 1.00 TSHR (0.46) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL8818200 1.00 TSHR (0.46) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL264171 1.00 TSHR (0.46) TSHRABCC4MAPTALDH1A1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220297157-A1 DNA SEQUENCING ASSEMBLIES AND MOLD ASSEMBLIES HAVING IMPROVED STABILITY IN AGGRESSIVE ENVIRONMENTS ACULON INC., 2022-09-22 US claimed
US-10185057-B2 Coated articles having abrasion resistant, glass-like coatings PPG INDUSTRIES OHIO, INC. (US) 2019-01-22 US claimed
EP-2776874-B1 COATED ARTICLES HAVING ABRASION RESISTANT, GLASS-LIKE COATINGS PPG IND OHIO INC (US) 2016-02-03 EP claimed
US-20080254995-A1 NANOPORE ARRAYS AND SEQUENCING DEVICES AND METHODS THEREOF DREXEL UNIVERSITY (US) 2008-10-16 US claimed
WO-1997048007-A1 DIPERSION-PREVENTING PATTERN FOR LIQUID CRYSTAL DISPLAY DEVICE THE DOW CHEMICAL COMPANY (US) 1997-12-18 WO claimed
US-5691011-A Dispersion-preventing pattern for liquid crystal display device THE DOW CHEMICAL COMPANY (US) 1997-11-25 US claimed
EP-0352180-B1 GLASS PANE PROVIDED WITH AN ANTI-ICE COATING SAINT-GOBAIN VITRAGE INTERNATIONAL (FR) 1992-12-30 EP claimed
US-5071709-A Surface treated with organo-halo silanes in non polar solvent system SAINT-GOBAIN VITRAGE (FR) 1991-12-10 US claimed
EP-0352180-A1 Glass pane provided with an anti-ice coating SAINT-GOBAIN VITRAGE INTERNATIONAL (FR) 1990-01-24 EP claimed
EP-4188489-B1 METHODS OF ALTERING THE SURFACE ENERGY OF COMPONENTS OF A MESH NEBULIZER ACULON INC (US) 2026-04-15 EP disclosed
US-12467577-B2 Fluidic channels and methods of altering the surface energy of components thereof ACULON, INC. 2025-11-11 US disclosed
US-20240142039-A1 FLUIDIC CHANNELS AND METHODS OF ALTERING THE SURFACE ENERGY OF COMPONENTS THEREOF ACULON, INC. (US) 2024-05-02 US disclosed
US-11867342-B2 Fluidic channels and methods of altering the surface energy of components thereof ACULON INC. (US) 2024-01-09 US disclosed
US-20230226261-A1 METHODS OF ALTERING THE SURFACE ENERGY OF COMPONENTS OF A MESH NEBULIZER AND MESH NEBULIZERS FORMED THEREBY ACULON, INC. (US) 2023-07-20 US disclosed
US-5455072-A Initiation and bonding of diamond and other thin films BENSION ROUVAIN M (US) 1995-10-03 US disclosed
EP-0598361-A1 Initiation and bonding of diamond and other thin films Bension, Rouvain M. (US) 1994-05-25 EP disclosed
EP-0352180-B1 GLASS PANE PROVIDED WITH AN ANTI-ICE COATING SAINT-GOBAIN VITRAGE INTERNATIONAL (FR) 1992-12-30 EP disclosed
US-5071709-A Surface treated with organo-halo silanes in non polar solvent system SAINT-GOBAIN VITRAGE (FR) 1991-12-10 US disclosed
EP-0352180-A1 Glass pane provided with an anti-ice coating SAINT-GOBAIN VITRAGE INTERNATIONAL (FR) 1990-01-24 EP disclosed
US-4539061-A CHEMISORPTION, ACTIVATION, MOLECULAR ORIENTATIN, BONDING YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 1985-09-03 US disclosed