SCHEMBL505783

SCHEMBL505783

CC(C)(C)[Si](C)(O)C(C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5005529 0.80
SCHEMBL29146 0.76
SCHEMBL28427971 0.73
Water SCHEMBL27495819 0.73
SCHEMBL8857028 0.73
SCHEMBL5609357 0.73
SCHEMBL838299 0.70
SCHEMBL2341763 0.70
SCHEMBL839019 0.67
SCHEMBL336868 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120029226-A1 METHOD FOR THE SYNTHESIS OF CHIRAL ALPHA-ARYL PROPIONIC ACID DERIVATIVES DSM IP ASSETS B.V. (NL) 2012-02-02 US claimed
US-8273726-B2 Compositions for treating and/or preventing diseases characterized by the presence of metal ions BRANDEIS UNIVERSITY (US) 2012-09-25 US disclosed
US-20100184724-A1 COMPOSITIONS FOR TREATING AND/OR PREVENTING DISEASES CHARACTERIZED BY THE PRESENCE OF METAL IONS GRENPHARMA LLC (US) 2010-07-22 US disclosed
EP-0926154-B1 NOVEL LACTOSAMINE OLIGOSACCHARIDES AND PROCESS FOR THE PREPARATION THEREOF SEIKAGAKU KOGYO CO LTD (JP) 2010-01-27 EP disclosed
US-7595308-B2 Treatment and/or prevention of Alzheimer's disease, other neurodegenerative diseases, and/or diseases characterized by the presence of certain metal ions, by using organosilicon compounds such as dichlorodiethylsilane GRENPHARMA LLC (US) 2009-09-29 US disclosed
US-20090203644-A1 Compositions for treating and/or preventing diseases characterized by the presence of metal ions GRENPHARMA LLC (US) 2009-08-13 US disclosed
US-6365733-B1 OLIGOSACCHARIDE PREPARED BY CLEAVING AND DESULFATING KERATIN SULFATE; ANTIINFLAMMATORY AGENTS; ANTICARCINOGENIC AGENTS; ANTIMETASTATIS AGENTS SEIKAGAKU CORPORATION (JP) 2002-04-02 US disclosed
US-6132994-A Lactosamine oligosaccharides and method for producing the same SEIKAGAKU CORPORATION (JP) 2000-10-17 US disclosed
EP-0926154-A1 NOVEL LACTOSAMINE OLIGOSACCHARIDES AND PROCESS FOR THE PREPARATION THEREOF SEIKAGAKU CORPORATION (JP) 1999-06-30 EP disclosed
US-5808112-A Preparation of cis-4-O-protected-2-cyclopentenol derivatives HOECHST MARION ROUSSEL INC. (US) 1998-09-15 US disclosed
US-5728899-A Preparation of cis-4-O-protected-2-cyclopentenol derivatives HOECHST MARION ROUSSEL INC. (US) 1998-03-17 US disclosed
EP-0817764-A1 PREPARATION OF CIS-4-O-PROTECTED-2-CYCLOPENTENOL DERIVATIVES HOECHST MARION ROUSSEL, INC. (US) 1998-01-14 EP disclosed
US-5691319-A ANTICARCINOGENIC AGENTS SANKYO COMPANY, LIMITED (JP) 1997-11-25 US disclosed
WO-1996030320-A1 PREPARATION OF CIS-4-O-PROTECTED-2-CYCLOPENTENOL DERIVATIVES HOECHST MARION ROUSSEL, INC. (US) 1996-10-03 WO disclosed
EP-0536936-B1 Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use SANKYO CO (JP) 1996-08-14 EP disclosed
EP-0536936-A1 Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use Sankyo Company Limited (JP) 1993-04-14 EP disclosed