Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17977267 | 0.83 | — | — | |
| SCHEMBL1361559 | 0.82 | S1PR5 (0.43) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL24952583 | 0.80 | SMN1; SMN2 (0.78) | SMN1; SMN2BCHEGAALTA4HKDM4E | |
| SCHEMBL12635335 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2BCHEGAALTA4HKDM4E | |
| SCHEMBL12635333 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2BCHEGAALTA4HKDM4E | |
| SCHEMBL23557639 | 0.80 | SMN1; SMN2 (0.78) | SMN1; SMN2BCHEGAALTA4HKDM4E | |
| SCHEMBL12524456 | 0.80 | SMN1; SMN2 (0.78) | SMN1; SMN2BCHEGAALTA4HKDM4E | |
| SCHEMBL14315095 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2BCHEGAALTA4HKDM4E | |
| SCHEMBL23855249 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2BCHEGAALTA4H | |
| SCHEMBL4730783 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2BCHEGAALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008007835-A1 | 2,4-QUINAZOLINE DERIVATIVES HAVING ACTIVITY TO T-TYPE CALCIUM CHANNEL AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-01-17 | — | — | WO | disclosed |