Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.48 |
| ▸ | PRKCI | P41743 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | QPCT | Q16769 | 2/20 | 0.46 |
| ▸ | QPCTL | Q9NXS2 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzimidazole SCHEMBL23673327 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2PDPK1CA12PARP1ALOX15 | |
| Benzimidazole SCHEMBL4252938 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2PDPK1CA12PARP1ALOX15 | |
| Benzimidazole SCHEMBL7255234 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2PDPK1CA12PARP1ALOX15 | |
| Benzimidazole SCHEMBL31503193 | 0.98 | SMN1; SMN2 (0.47) | SMN1; SMN2PDPK1CA12PARP1ALOX15 | |
| Benzimidazole SCHEMBL28252533 | 0.98 | KDM4E (0.50) | SMN1; SMN2PDPK1CA12PARP1ALOX15 | |
| Benzimidazole SCHEMBL28283376 | 0.98 | SMN1; SMN2 (0.47) | SMN1; SMN2PDPK1CA12PARP1ALOX15 | |
| Benzimidazole SCHEMBL6009 | 0.97 | — | — | |
| Benzimidazole SCHEMBL29358377 | 0.97 | — | — | |
| Benzimidazole SCHEMBL10931770 | 0.97 | SMN1; SMN2 (0.50) | SMN1; SMN2PDPK1CA12PARP1ALOX15 | |
| Benzimidazole SCHEMBL29408372 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330886-A | Benzimidazole amine derivative, preparation method thereof and beta2Use of allosteric antagonists of adrenergic receptors | 常州大学 | 2025-01-21 | — | — | CN | claimed |
| CN-119318653-A | Application of benzimidazole amine derivatives in medicines for preventing/treating non-alcoholic fatty liver disease | 常州大学 | 2025-01-17 | — | — | CN | claimed |
| CN-115721606-B | Micelle, preparation method thereof and pharmaceutical composition comprising micelle | 博美利克斯技术公司 | 2024-09-13 | — | — | CN | claimed |
| CN-118039923-A | High-temperature membrane fuel cell electrode capable of enhancing oxygen transmission performance and preparation method | 江苏大学 | 2024-05-14 | — | — | CN | claimed |
| CN-117402148-A | Nitrogen-nitrogen benzimidazole axial chiral compound, and preparation method and application thereof | 青岛大学 | 2024-01-16 | — | — | CN | claimed |
| CN-113930221-B | Special coolant for diesel locomotive | 常州市鑫光新材料科技有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-116919953-A | Application of benzimidazole amine derivative in preparation of antitumor pharmaceutical composition | 广西科技大学 | 2023-10-24 | — | — | CN | claimed |
| CN-116322079-A | Solar cell device and preparation method and application thereof | 无锡极电光能科技有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-115721606-A | Micelle, preparation method thereof and pharmaceutical composition comprising same | 博美利克斯技术公司 | 2023-03-03 | — | — | CN | claimed |
| WO-2023027236-A1 | MICELLE COMPRISING BENZIMIDAZOLE-CARBOHYDRATE CONJUGATE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF AS ANTICANCER AGENT OR ANTIVIRAL AGENT | (주)바이오메트릭스 테크놀로지 | 2023-03-02 | — | — | WO | claimed |
| EP-1730113-B1 | PROCESS FOR THE SYNTHESIS OF A CXCR4 ANTAGONIST | GENZYME CORP (US) | 2016-12-28 | — | — | EP | claimed |
| CN-104416996-B | A kind of PET film having ball-type graphite linings and preparation method thereof | 天津安品有机硅材料有限公司 | 2016-09-07 | — | — | CN | claimed |
| CN-103079685-B | For the anisotropic membrane of nanofiltration | IMPERIAL INNOVATIONS LTD. (GB) | 2016-03-30 | — | — | CN | claimed |
| CN-103079685-A | Asymmetric membranes for use in nanofiltration | IMP INNOVATIONS LTD | 2013-05-01 | — | — | CN | claimed |
| CN-102803442-A | Method for removing metals from hydrocarbons | PETROLIAM NASIONAL BERHAD | 2012-11-28 | — | — | CN | claimed |
| US-7332605-B2 | Process for the synthesis of CXCR4 antagonist | ANORMED, INC. (CA) | 2008-02-19 | — | — | US | claimed |
| WO-2007078034-A1 | A COMPOSITION FOR INHIBITING THE C-KIT PORTEIN CONTAINING BENZIMIDAZOLE AMINE DERIVATIVES OR AMINOQUINOLINE DERIVATIVES | AMOREPACIFIC CORPORATION (KR) | 2007-07-12 | — | — | WO | claimed |
| EP-1730113-A1 | PROCESS FOR THE SYNTHESIS OF A CXCR4 ANTAGONIST | ANORMED INC. (CA) | 2006-12-13 | — | — | EP | claimed |
| WO-2005090308-A1 | PROCESS FOR THE SYNTHESIS OF A CXCR4 ANTAGONIST | ANORMED, INC. (CA) | 2005-09-29 | — | — | WO | claimed |
| US-20050209277-A1 | Process for the synthesis of CXCR4 antagonist | ANORMED CORPORATION (CA) | 2005-09-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209277-A1 | Process for the synthesis of CXCR4 antagonist | CXCR4, CXCR1, CXCL12 | SMN1; SMN2 3919/4885PDPK1 1877/4885CA12 3598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.