SCHEMBL5059751

SCHEMBL5059751

[CH2]CNC(=O)CS

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12473533 0.78
SCHEMBL928768 0.75
SCHEMBL5669318 0.75 HDAC6 (0.42)
SCHEMBL67112 0.73
SCHEMBL7565642 0.73
SCHEMBL3895083 0.71
SCHEMBL294551 0.71
SCHEMBL929676 0.71
SCHEMBL1040561 0.71
SCHEMBL18696265 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0300665-B1 Cephalosporin compounds, process for their preparation and their pharmaceutical compositions ZENECA PHARMA SA (FR) 1995-12-20 EP claimed
EP-0304155-B1 Cephalosporin compounds, process for their preparation and their pharmaceutical compositions ZENECA PHARMA SA (FR) 1995-11-15 EP claimed
EP-0225182-B1 CEPHALOSPORIN COMPOUNDS ICI PHARMA (FR) 1993-02-10 EP claimed
US-5013731-A Bactericides ICI PHARMA (FR) 1991-05-07 US claimed
US-5008258-A Antibiotics I.C.I.-PHARMA (FR) 1991-04-16 US claimed
EP-0164944-B1 CEPHALOSPORIN DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-07-11 EP claimed
US-4868173-A CONTAIN AMINE SALT GROUP ICI PHARMA (FR) 1989-09-19 US claimed
EP-0304155-A2 Cephalosporin compounds, process for their preparation and their pharmaceutical compositions ZENECA Pharma S.A. (FR) 1989-02-22 EP claimed
EP-0300664-A2 Cephalosporin compounds ZENECA Pharma S.A. (FR) 1989-01-25 EP claimed
EP-0300665-A2 Cephalosporin compounds, process for their preparation and their pharmaceutical compositions ZENECA Pharma S.A. (FR) 1989-01-25 EP claimed
EP-0225182-A2 Cephalosporin compounds ICI PHARMA (FR) 1987-06-10 EP claimed
EP-0182633-A2 Cephalosporin derivatives ICI PHARMA (FR) 1986-05-28 EP claimed
EP-0164944-A1 Cephalosporin derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-12-18 EP claimed
US-9446109-B2 Glycoconjugates and their use as potential vaccines against infection by Shigella flexneri INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2016-09-20 US disclosed
US-20140161793-A2 GLYCOCONJUGATES AND THEIR USE AS POTENTIAL VACCINES AGAINST INFECTION BY SHIGELLA FLEXNERI INSERM (FR) 2014-06-12 US disclosed
US-20130243751-A1 GLYCOCONJUGATES AND THEIR USE AS POTENTIAL VACCINES AGAINST INFECTION BY SHIGELLA FLEXNERI CNRS (CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE 2013-09-19 US disclosed
EP-0215355-A2 Erythromycin derivative and process for preparing the same KITASATO KENKYUSHO (JP) 1987-03-25 EP disclosed
EP-0213617-A2 Digestive tract contractile motion stimulant KITASATO KENKYUSHO (JP) 1987-03-11 EP disclosed
EP-0182633-A2 Cephalosporin derivatives ICI PHARMA (FR) 1986-05-28 EP disclosed
EP-0164944-A1 Cephalosporin derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-12-18 EP disclosed