Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 4/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5059750 | 0.85 | CETP (0.32) | CETPMMP1MMP2MMP3 | |
| SCHEMBL5059757 | 0.80 | CETP (0.32) | CETPMMP1MMP2MMP3 | |
| SCHEMBL5054812 | 0.78 | CYSLTR2 (0.39) | CYSLTR2CYSLTR1CETPFOLH1 | |
| SCHEMBL5059889 | 0.72 | FOLH1 (0.36) | MMP1MMP2MMP3FOLH1 | |
| SCHEMBL5051255 | 0.72 | HDAC3 (0.38) | FOLH1 | |
| SCHEMBL6037795 | 0.68 | CETP (0.34) | CETPMMP1 | |
| SCHEMBL5051174 | 0.68 | CETP (0.38) | CETPMMP2MMP3 | |
| SCHEMBL5053060 | 0.67 | CETP (0.39) | CETP | |
| SCHEMBL5053290 | 0.67 | LPAR1 (0.31) | — | |
| SCHEMBL5053022 | 0.67 | GGH (0.40) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080311037-A1 | Compounds which bind PSMA and uses thereof | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080311037-A1 | Compounds which bind PSMA and uses thereof | FOLH1, PSMA1, BPHL | CYSLTR2 1905/4885CYSLTR1 1054/4885CETP 1402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.