Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 8/20 | 0.59 |
| ▸ | KDR | P35968 | 7/20 | 0.58 |
| ▸ | CSF1R | P07333 | 7/20 | 0.55 |
| ▸ | MET | P08581 | 5/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.55 |
| ▸ | FLT3 | P36888 | 4/20 | 0.55 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5055159 | 0.92 | AXL (0.61) | AXLKDRCSF1RMETPDGFRA | |
| SCHEMBL5052206 | 0.92 | KDR (0.56) | AXLKDRCSF1RMETPDGFRA | |
| SCHEMBL5055314 | 0.90 | KDR (0.54) | AXLKDRCSF1RMETPDGFRA | |
| SCHEMBL5059967 | 0.88 | KDR (0.60) | AXLKDRCSF1RMETPDGFRA | |
| SCHEMBL5062260 | 0.88 | KDR (0.54) | AXLKDRCSF1RMETPDGFRA | |
| SCHEMBL5060620 | 0.88 | KDR (0.54) | AXLKDRCSF1RMETPDGFRA | |
| SCHEMBL5140140 | 0.88 | KDR (0.51) | AXLKDRRAF1 | |
| SCHEMBL5052271 | 0.87 | KDR (0.52) | AXLKDRCSF1RMETPDGFRA | |
| SCHEMBL5056345 | 0.86 | KDR (0.52) | AXLKDRCSF1RMETPDGFRA | |
| SCHEMBL5054777 | 0.86 | KDR (0.52) | AXLKDRCSF1RMETPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113967-A1 | ENZYME MODULATORS AND TREATMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2008-05-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113967-A1 | ENZYME MODULATORS AND TREATMENTS | ABL2, BRAF, MAP3K1 | AXL 117/4885KDR 41/4885CSF1R 979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.