SCHEMBL5064035

SCHEMBL5064035

O=C(O)C1=CNC=CC=N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27506717 0.79 HDAC1 (0.31)
SCHEMBL1505973 0.71
SCHEMBL6064585 0.64 MEN1 (0.42)
SCHEMBL5801459 0.64
SCHEMBL5803595 0.64
SCHEMBL19745643 0.62
SCHEMBL193861 0.61
Benzene SCHEMBL28096982 0.60
SCHEMBL12957552 0.60
Hydrochloric Acid SCHEMBL27969702 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220079952-A1 Uses of Radiation and Benzodiazepine Derivatives in Cancer Therapies UNIV EMORY (US) 2022-03-17 US disclosed
EP-1888594-A2 GABAERGIC AGENTS TO TREAT MEMORY DEFICITS WISYS TECHNOLOGY FOUNDATION, INC. (US) 2008-02-20 EP disclosed
WO-2007018660-A2 GABAERGIC IMIDAZOBENZODIAZEPINE DERIVATIVES TO TREAT MEMORY DEFICITS WISYS TECHNOLOGY FOUNDATION, INC. (US) 2007-02-15 WO disclosed
EP-1490344-A2 ANXIOLYTIC AGENTS WITH REDUCED SEDATIVE AND ATAXIC EFFECTS Wisys Technology Foundation, Inc. (US) 2004-12-29 EP disclosed
EP-1440057-A1 ALLENIC ARYL SULFONAMIDE HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE AND TACE INHIBITORS Wyeth Holdings Corporation (US) 2004-07-28 EP disclosed
WO-2003082832-A2 ANXIOLYTIC AGENTS WITH REDUCED SEDATIVE AND ATAXIC EFFECTS WISYS TECHNOLOGY FOUNDATION, INC. (US) 2003-10-09 WO disclosed
WO-2003037852-A1 ALLENIC ARYL SULFONAMIDE HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE AND TACE INHIBITORS WYETH HOLDINGS CORPORATION (US) 2003-05-08 WO disclosed