Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 14/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | WNT1 | P04628 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 8/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 8/20 | 0.39 |
| ▸ | KDR | P35968 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 2/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | MET | P08581 | 3/20 | 0.38 |
| ▸ | FLT3 | P36888 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3666984 | 0.88 | CSF1R (0.40) | CSF1RGSK3BDYRK1AWNT1PDGFRB | |
| SCHEMBL3664410 | 0.88 | CSF1R (0.45) | CSF1RGSK3BDYRK1AWNT1PDGFRB | |
| SCHEMBL572506 | 0.84 | AXL (0.51) | CSF1RPDGFRBPDGFRAKDRCYP2C9 | |
| SCHEMBL5060896 | 0.82 | CSF1R (0.42) | CSF1RPDGFRBPDGFRAKDRCYP2C9 | |
| SCHEMBL3660380 | 0.82 | KDR (0.48) | CSF1RPDGFRBPDGFRAKDRCYP2C9 | |
| SCHEMBL3632908 | 0.81 | CSF1R (0.43) | CSF1RPDGFRBPDGFRAKDRCYP2C9 | |
| SCHEMBL3806703 | 0.81 | KDR (0.45) | CSF1RPDGFRBPDGFRAKDRCYP2C9 | |
| SCHEMBL5064074 | 0.80 | CSF1R (0.43) | CSF1RPDGFRBPDGFRAKDRCYP2C9 | |
| SCHEMBL3667357 | 0.80 | CSF1R (0.44) | CSF1RPDGFRBPDGFRAKDRCYP2C9 | |
| SCHEMBL3664223 | 0.79 | KDR (0.53) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269254-A1 | KINASE INHIBITORS USEFUL FOR THE TREATMENT OF MYLEOPROLIFIC DISEASES AND OTHER PROLIFERATIVE DISEASES | DECIPHERA PHARMACEUTICALS, LLC (US) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269254-A1 | KINASE INHIBITORS USEFUL FOR THE TREATMENT OF MYLEOPROLIFIC DISEASES AND OTHER PROLIFERATIVE DISEASES | KIT, BRAF, RET | CSF1R 170/4885GSK3B 1766/4885DYRK1A 675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.