⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL29828716 | 0.97 | — | — | |
| Valine SCHEMBL31618928 | 0.97 | — | — | |
| Valine SCHEMBL41225 | 0.97 | SLC7A5 (1.00) | — | |
| Valine SCHEMBL43678 | 0.97 | — | — | |
| Valine SCHEMBL8515 | 0.97 | — | — | |
| Valine SCHEMBL288203 | 0.97 | SLC7A5 (1.00) | — | |
| Valine SCHEMBL2785563 | 0.97 | SLC7A5 (1.00) | — | |
| Valine SCHEMBL1813972 | 0.97 | SLC7A5 (1.00) | — | |
| Valine SCHEMBL8516 | 0.97 | — | — | |
| Valine SCHEMBL29622105 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080152640-A1 | Means and Methods For Treating a Disease Which is Associated With an Excess Transport of Hyaluronan Across a Lipid Bilayer | UNIVERSITATSKLINIKUM MUNSTER (DE) | 2008-06-26 | — | — | US | disclosed |
| EP-1660072-A2 | MEANS AND METHODS FOR TREATING A DISEASE WHICH IS ASSOCIATED WITH AN EXCESS TRANSPORT OF HYALURONAN ACROSS A LIPID BILAYER | Universitätsklinikum Münster (DE) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005013947-A2 | MEANS AND METHODS FOR TREATING A DISEASE WHICH IS ASSOCIATED WITH AN EXCESS TRANSPORT OF HYALURONAN ACROSS A LIPID BILAYER | Universitätsklinikum Münster (DE) | 2005-02-17 | — | — | WO | disclosed |
| EP-0874991-A1 | METHOD OF SELECTING A POPULATION OR SUBPOPULATION OF A SAMPLE UTILIZING PARTICLE AND GRAVITY SEDIMENTATION | Coulter International Corp. (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997018474-A1 | METHOD OF SELECTING A POPULATION OR SUBPOPULATION OF A SAMPLE UTILIZING PARTICLE AND GRAVITY SEDIMENTATION | COULTER INTERNATIONAL CORP. (US) | 1997-05-22 | — | — | WO | disclosed |
| US-4454870-A | Halo jig | ACE MEDICAL COMPANY (US) | 1984-06-19 | — | — | US | disclosed |