Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4292235 | 0.92 | CHEK1 (0.85) | CHEK1CDK7 | |
| SCHEMBL4289319 | 0.92 | CHEK1 (0.83) | CHEK1CDK7 | |
| SCHEMBL4289821 | 0.91 | CHEK1 (0.76) | CHEK1CDK7 | |
| SCHEMBL4297857 | 0.90 | CHEK1 (0.75) | CHEK1CDK7 | |
| SCHEMBL4296368 | 0.89 | CHEK1 (0.85) | CHEK1CDK7 | |
| SCHEMBL4290285 | 0.88 | CHEK1 (1.00) | CHEK1CDK7 | |
| SCHEMBL4289875 | 0.87 | CHEK1 (0.83) | CHEK1CDK7 | |
| SCHEMBL4298034 | 0.87 | CHEK1 (0.81) | CHEK1CDK7 | |
| SCHEMBL4298040 | 0.87 | CHEK1 (0.81) | CHEK1CDK7 | |
| SCHEMBL4297854 | 0.87 | CHEK1 (0.79) | CHEK1CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893607-A2 | INHIBITORS OF CHECKPOINT KINASES | Merck & Co., Inc. (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006135604-A2 | INHIBITORS OF CHECKPOINT KINASES | MERCK & CO., INC. (US) | 2006-12-21 | — | — | WO | disclosed |