Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3631368 | 0.77 | KDR (0.43) | RAF1 | |
| SCHEMBL826840 | 0.77 | KDR (0.45) | — | |
| SCHEMBL5064101 | 0.67 | MAPK14 (0.37) | RAF1 | |
| SCHEMBL5065440 | 0.65 | KDR (0.42) | RAF1 | |
| SCHEMBL2447423 | 0.65 | CSF1R (0.40) | — | |
| SCHEMBL3659669 | 0.64 | KDR (0.43) | RAF1 | |
| SCHEMBL3660380 | 0.63 | KDR (0.48) | RAF1 | |
| SCHEMBL3658869 | 0.63 | KDR (0.44) | RAF1 | |
| SCHEMBL3663211 | 0.62 | KDR (0.42) | RAF1 | |
| SCHEMBL5068759 | 0.61 | KDR (0.42) | RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269254-A1 | KINASE INHIBITORS USEFUL FOR THE TREATMENT OF MYLEOPROLIFIC DISEASES AND OTHER PROLIFERATIVE DISEASES | DECIPHERA PHARMACEUTICALS, LLC (US) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269254-A1 | KINASE INHIBITORS USEFUL FOR THE TREATMENT OF MYLEOPROLIFIC DISEASES AND OTHER PROLIFERATIVE DISEASES | KIT, BRAF, RET | RAF1 20/4885MAP2K1 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.