Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 1/20 | 0.67 |
| ▸ | FNTA | P49354 | 5/20 | 0.65 |
| ▸ | FNTB | P49356 | 3/20 | 0.65 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.56 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10452622 | 1.00 | BTN3A1 (0.67) | BTN3A1FNTAFNTBPGGT1BGGPS1 | |
| SCHEMBL6550564 | 1.00 | BTN3A1 (0.67) | BTN3A1FNTAFNTBPGGT1BGGPS1 | |
| SCHEMBL6550557 | 1.00 | BTN3A1 (0.67) | BTN3A1FNTAFNTBPGGT1BGGPS1 | |
| SCHEMBL10452972 | 0.90 | FNTA (0.57) | FNTAFNTB | |
| SCHEMBL10452973 | 0.90 | FNTA (0.57) | FNTAFNTB | |
| SCHEMBL7926828 | 0.87 | BTN3A1 (0.63) | BTN3A1FNTAFNTBPGGT1BGGPS1 | |
| SCHEMBL7926829 | 0.87 | BTN3A1 (0.63) | BTN3A1FNTAFNTBPGGT1BGGPS1 | |
| SCHEMBL7926830 | 0.87 | BTN3A1 (0.63) | BTN3A1FNTAFNTBPGGT1BGGPS1 | |
| SCHEMBL9473591 | 0.87 | FNTA (0.62) | BTN3A1FNTAFNTBPGGT1BGGPS1 | |
| SCHEMBL9473586 | 0.87 | FNTA (0.62) | BTN3A1FNTAFNTBPGGT1BGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4871721-A | HYPOCHOLESTEROLEMIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1989-10-03 | — | — | US | claimed |
| EP-0324421-A2 | Phosporus-containing squalene synthetase inhibitors, new intermediates and method | E.R. Squibb & Sons, Inc. (US) | 1989-07-19 | — | — | EP | claimed |
| JP-1213288-A | — | — | None | — | — | JP | disclosed |
| US-20080214471-A1 | Method for inhibition of viral infection | Glenn, M.D., Jeffrey S. | 2008-09-04 | — | — | US | disclosed |
| US-20060040259-A1 | Method for inhibition of viral infection | GLENN JEFFREY S | 2006-02-23 | — | — | US | disclosed |
| US-20030181355-A1 | Method for inhibition of viral infection | GLENN JEFFREY S (US) | 2003-09-25 | — | — | US | disclosed |
| US-5567729-A | USED TO REDUCE THE LEVEL OF PROTEIN FARNESYLATION IN MAMMALS | Bradfute, David L. (US) | 1996-10-22 | — | — | US | disclosed |
| US-4924024-A | ANTICHOLESTEROL AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1990-05-08 | — | — | US | disclosed |
| US-4871721-A | HYPOCHOLESTEROLEMIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1989-10-03 | — | — | US | disclosed |
| JP-H01213288-A | PHOSPHOROUS-CONTAINING SQUALENE SYNTHETASE INHIBITOR, ITS PREPARATION AND ITS NEW INTERMEDIATE | E R SQUIBB & SONS INC | 1989-08-28 | — | — | JP | disclosed |
| EP-0324421-A2 | Phosporus-containing squalene synthetase inhibitors, new intermediates and method | E.R. Squibb & Sons, Inc. (US) | 1989-07-19 | — | — | EP | disclosed |