Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 17/20 | 0.80 |
| ▸ | ITGA4 | P13612 | 17/20 | 0.80 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5071004 | 0.91 | ITGB1 (0.78) | ITGB1ITGA4KDM4EMEN1ALDH1A1 | |
| SCHEMBL5068351 | 0.90 | ITGB1 (0.82) | ITGB1ITGA4KDM4EMAPTRAB9A | |
| SCHEMBL5068926 | 0.89 | ITGB1 (1.00) | ITGB1ITGA4 | |
| SCHEMBL5066874 | 0.89 | ITGB1 (1.00) | ITGB1ITGA4 | |
| SCHEMBL5068391 | 0.81 | ITGB1 (0.77) | ITGB1ITGA4 | |
| SCHEMBL5070985 | 0.81 | ITGB1 (1.00) | ITGB1ITGA4 | |
| SCHEMBL5066854 | 0.80 | ITGB1 (0.83) | ITGB1ITGA4 | |
| SCHEMBL5068415 | 0.79 | ITGB1 (0.81) | ITGB1ITGA4 | |
| SCHEMBL5069258 | 0.77 | ITGB1 (1.00) | ITGB1ITGA4 | |
| SCHEMBL5068355 | 0.77 | ITGB1 (0.78) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410984-B2 | Compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-08-12 | — | — | US | claimed |