Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5689961 | 0.90 | TSHR (0.63) | TSHRCYP3A4TDP1ATMNAAA | |
| SCHEMBL11133782 | 0.90 | TSHR (0.56) | TSHRCYP3A4TDP1ATMNAAA | |
| SCHEMBL20609794 | 0.84 | TSHR (1.00) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL29596375 | 0.84 | TSHR (1.00) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL16765797 | 0.84 | TSHR (1.00) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL14869 | 0.84 | TSHR (1.00) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL27646321 | 0.84 | TSHR (0.72) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| Hydrochloric Acid SCHEMBL10432463 | 0.83 | TSHR (0.97) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| Bromide SCHEMBL20490069 | 0.83 | TSHR (0.97) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL31738423 | 0.83 | TSHR (0.97) | TSHRCYP3A4TDP1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0141610-A2 | Optical elements comprising polymers of (meth)acrylate esters | Hitachi Chemical Co., Ltd. (JP) | 1985-05-15 | — | — | EP | claimed |
| EP-1781741-B1 | CURABLE ORGANOPOLYSILOXANE COMPOSITION, METHOD OF CURING THEREOF, SEMICONDUCTOR DEVICE, AND ADHESION PROMOTER | DOW CORNING TORAY CO LTD (JP) | 2008-08-27 | — | — | EP | disclosed |
| EP-0875142-B1 | Stable pesticide dispersions | ROHM & HAAS (US) | 2003-07-02 | — | — | EP | disclosed |
| US-6210696-B1 | Stable pesticide dispersions | ROHM AND HAAS COMPANY | 2001-04-03 | — | — | US | disclosed |
| EP-0875142-A2 | Stable presticide dispersions | ROHM AND HAAS COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |
| EP-0454980-B1 | Encapsulated toners and processes thereof | XEROX CORP (US) | 1998-08-05 | — | — | EP | disclosed |
| EP-0436080-B1 | Core-shell polymer and its use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-01-10 | — | — | EP | disclosed |
| US-5280075-A | Core is blend butadiene-styrene copolymer, alkyl acrylate; shellis acrylonitrile-styrene copolymer and alkyl methacrylate | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-01-18 | — | — | US | disclosed |
| US-5139915-A | ENCAPSULATED TONERS AND PROCESSES THEREOF | XEROX CORPORATION (US) | 1992-08-18 | — | — | US | disclosed |
| EP-0454980-A1 | Encapsulated toners and processes thereof | XEROX CORPORATION (US) | 1991-11-06 | — | — | EP | disclosed |
| EP-0436080-A2 | Core-shell polymer and its use | Takeda Chemical Industries, Ltd. (JP) | 1991-07-10 | — | — | EP | disclosed |