Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1338821 | 1.00 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2MAPK1MAPT | |
| SCHEMBL1338546 | 0.84 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2MAPK1MAPT | |
| SCHEMBL1337583 | 0.80 | MAPT (0.65) | NPC1RAB9ASMN1; SMN2MAPK1MAPT | |
| SCHEMBL14352056 | 0.77 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2MAPK1MAPT | |
| SCHEMBL6578393 | 0.77 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2MAPK1MAPT | |
| SCHEMBL31037188 | 0.77 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2MAPK1MAPT | |
| SCHEMBL14154795 | 0.77 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2MAPK1MAPT | |
| SCHEMBL14821250 | 0.77 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2MAPK1MAPT | |
| SCHEMBL1338846 | 0.76 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL18083719 | 0.75 | MAPK1 (0.52) | NPC1RAB9ASMN1; SMN2MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1956012-A1 | METHOD FOR PRODUCING 2-OXAZOLINE ANALOGUE OR 1,3-OXAZINE ANALOGUE | National University Corporation Hokkaido University (JP) | 2008-08-13 | — | — | EP | disclosed |