Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.67 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10355787 | 0.96 | CA1 (0.73) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL9123559 | 0.96 | CA1 (0.73) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL30956907 | 0.96 | CA1 (0.73) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL7540275 | 0.96 | CA1 (0.73) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL28493690 | 0.96 | CA1 (0.73) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL9340215 | 0.96 | CA1 (0.73) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL28321513 | 0.96 | CA1 (0.73) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL28942880 | 0.92 | CA1 (0.75) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL28364495 | 0.92 | CA1 (0.75) | CA1FFAR3LCKFYNCA4 | |
| Acetic Acid SCHEMBL28761021 | 0.92 | CA1 (0.67) | CA1FFAR3LCKFYNCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430185-A | Process for manufacturing crystalline calcium magnesium acetate | GENERAL ATOMICS INTERNATIONAL SERVICES CORPORATION (US) | 1995-07-04 | — | — | US | claimed |
| EP-1877565-A2 | ANAEROBIC PRODUCTION OF HYDROGEN AND OTHER CHEMICAL PRODUCTS | Anaerobe Systems (US) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006119052-A2 | ANAEROBIC PRODUCTION OF HYDROGEN AND OTHER CHEMICAL PRODUCTS | ANAEROBE SYSTEMS (US) | 2006-11-09 | — | — | WO | disclosed |