⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2764900 | 1.00 | — | — | |
| SCHEMBL5069815 | 1.00 | — | — | |
| SCHEMBL10869939 | 0.97 | TSHR (0.40) | — | |
| SCHEMBL10870784 | 0.97 | TSHR (0.40) | — | |
| SCHEMBL1261809 | 0.97 | TSHR (0.40) | — | |
| SCHEMBL10870835 | 0.97 | TSHR (0.40) | — | |
| SCHEMBL6472048 | 0.97 | TSHR (0.40) | — | |
| SCHEMBL10869461 | 0.97 | TSHR (0.40) | — | |
| SCHEMBL10870055 | 0.97 | TSHR (0.40) | — | |
| SCHEMBL10868788 | 0.97 | TSHR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756271-B1 | METHODS FOR OBTAINING OPTICALLY ACTIVE EPOXIDES AND VICINAL DIOLS FROM 2,2-DISUBSTITUTED EPOXIDES | CSIR (ZA) | 2015-12-09 | — | — | EP | disclosed |
| US-20080286832-A1 | Methods for Obtaining Optically Active Epoxides and Vicinal Diols From 2,2-Disubstituted Epoxides | COUNCIL FOR SCIENTIFIC AND INDUSTRIAL RESEARCH (ZA) | 2008-11-20 | — | — | US | disclosed |
| EP-1756271-A2 | METHODS FOR OBTAINING OPTICALLY ACTIVE EPOXIDES AND VICINAL DIOLS FROM 2,2-DISUBSTITUTED EPOXIDES | CSIR (ZA) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005100587-A2 | METHODS FOR OBTAINING OPTICALLY ACTIVE EPOXIDES AND VICINAL DIOLS FROM 2,2-DISUBSTITUTED EPOXIDES | CSIR (ZA) | 2005-10-27 | — | — | WO | disclosed |