Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | IGF1R | P08069 | 3/20 | 0.41 |
| ▸ | FLT4 | P35916 | 3/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 6/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810574 | 0.90 | MAOB (0.49) | KDM4EALDH1A1MAPTHPGDSLC6A2 | |
| SCHEMBL4389623 | 0.89 | NPC1 (0.48) | SLC6A2SLC6A4EGFRIGF1RFLT4 | |
| SCHEMBL5064972 | 0.89 | MAOB (0.42) | KDM4EALDH1A1MAPTHPGDSLC6A2 | |
| SCHEMBL4973845 | 0.81 | SIRT2 (0.41) | SLC6A2SLC6A4MAOBMAOASIRT2 | |
| SCHEMBL811689 | 0.80 | MAOB (0.54) | MAOBMAOA | |
| SCHEMBL811162 | 0.80 | CACNA1C (0.51) | KDM4EALDH1A1MAPTHPGDSLC6A2 | |
| SCHEMBL810264 | 0.78 | SLC6A2 (0.43) | KDM4EALDH1A1MAPTHPGDSLC6A2 | |
| SCHEMBL810135 | 0.78 | MAPT (0.48) | KDM4EALDH1A1MAPTHPGDSLC6A2 | |
| SCHEMBL810527 | 0.78 | MAOB (0.44) | KDM4EALDH1A1MAPTHPGDSLC6A2 | |
| SCHEMBL810140 | 0.78 | MAOB (0.46) | SLC6A2SLC6A4MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971611-A1 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007081517-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-19 | — | — | WO | disclosed |