Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 9/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LGMN | Q99538 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1587720 | 0.86 | CETP (0.41) | CETPL3MBTL1PDK2MAPTKMT2A | |
| SCHEMBL1587680 | 0.83 | CETP (0.44) | CETPL3MBTL1PDK2 | |
| SCHEMBL1587600 | 0.82 | CETP (0.49) | CETPL3MBTL1PDK2LGMN | |
| SCHEMBL1587798 | 0.79 | CETP (0.39) | CETPPDK2 | |
| SCHEMBL13910237 | 0.79 | CETP (0.41) | CETPL3MBTL1PDK2LGMNMEN1 | |
| SCHEMBL1588251 | 0.78 | CETP (0.46) | CETP | |
| SCHEMBL132026 | 0.77 | CETP (0.45) | CETPL3MBTL1MEN1KMT2A | |
| SCHEMBL1587641 | 0.77 | CETP (0.40) | CETP | |
| SCHEMBL1588631 | 0.76 | CETP (0.51) | CETPL3MBTL1 | |
| SCHEMBL1587799 | 0.76 | CETP (0.51) | CETPL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979331-A1 | TRISUBSTITUTED AMINE COMPOUNDS AS INHIBITORS OF -CHOLESTERYL ESTER TRANSFER PROTEIN CETP | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007088996-A1 | TRISUBSTITUTED AMINE COMPOUNDS AS INHIBITORS OF -CHOLESTERYL ESTER TRANSFER PROTEIN CETP | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-08-09 | — | — | WO | disclosed |