Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.64 |
| ▸ | NPY1R | P25929 | 2/20 | 0.52 |
| ▸ | NPY2R | P49146 | 2/20 | 0.52 |
| ▸ | NPY4R | P50391 | 2/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.52 |
| ▸ | GLP1R | P43220 | 4/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.50 |
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | CTSH | P09668 | 1/20 | 0.50 |
| ▸ | GCGR | P47871 | 3/20 | 0.50 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.50 |
| ▸ | NMBR | P28336 | 1/20 | 0.50 |
| ▸ | GRPR | P30550 | 1/20 | 0.50 |
| ▸ | APLNR | P35414 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | MC5R | P33032 | 1/20 | 0.50 |
| ▸ | MC3R | P41968 | 1/20 | 0.50 |
| ▸ | MC1R | Q01726 | 1/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4956503 | 0.90 | GLP1R (0.61) | C5AR1NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL29660814 | 0.81 | C5AR1 (0.79) | C5AR1NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL29660777 | 0.81 | C5AR1 (0.79) | C5AR1NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL30116704 | 0.80 | C5AR1 (0.71) | C5AR1NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL29965030 | 0.80 | C5AR1 (0.74) | C5AR1NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL30495765 | 0.80 | NPY2R (0.64) | NPY1RNPY2RNPY4RNPY5RTFPI | |
| SCHEMBL30392901 | 0.80 | C5AR1 (0.65) | C5AR1NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL31574325 | 0.79 | C5AR1 (0.68) | C5AR1GLP1RGCGREPHA2APLNR | |
| SCHEMBL29880330 | 0.78 | C5AR1 (0.64) | C5AR1NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL31593288 | 0.78 | C5AR1 (0.63) | C5AR1NPY1RNPY2RNPY4RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080305998-A1 | Ligand to GPR8 and DNA thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2008-12-11 | — | — | US | disclosed |