Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5070221 | 0.84 | AR (0.54) | ARCYP19A1 | |
| SCHEMBL5073682 | 0.77 | AR (0.41) | AR | |
| SCHEMBL5069439 | 0.69 | AR (0.36) | ARCYP19A1ESR2ESR1SHBG | |
| SCHEMBL5069357 | 0.68 | AR (0.54) | ARCYP19A1 | |
| SCHEMBL5070199 | 0.68 | AR (0.54) | ARCYP19A1 | |
| SCHEMBL5071038 | 0.68 | AR (0.38) | ARCYP19A1ESR2ESR1SHBG | |
| SCHEMBL5070903 | 0.67 | AR (0.54) | AR | |
| SCHEMBL5070947 | 0.67 | AR (0.54) | AR | |
| SCHEMBL5070949 | 0.67 | AR (0.54) | AR | |
| SCHEMBL5070986 | 0.66 | AR (0.65) | ARCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467739-A4 | 17-HYDROXY-4-AZA-ANDROSTAN-3-ONES AS ANDROGEN RECEPTOR MODULATORS | MERCK & CO INC (US) | 2008-01-09 | — | — | EP | claimed |
| EP-1467739-A2 | 17-HYDROXY-4-AZA-ANDROSTAN-3-ONES AS ANDROGEN RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2004-10-20 | — | — | EP | claimed |
| WO-2003059293-A2 | 17-HYDROXY-4-AZA-ANDROSTAN-3-ONES AS ANDROGEN RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-07-24 | — | — | WO | claimed |