⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2746231 | 0.74 | — | — | |
| SCHEMBL5378825 | 0.72 | — | — | |
| SCHEMBL283912 | 0.72 | — | — | |
| SCHEMBL8123470 | 0.70 | — | — | |
| SCHEMBL3589631 | 0.70 | — | — | |
| SCHEMBL22791820 | 0.70 | — | — | |
| SCHEMBL7905677 | 0.70 | — | — | |
| SCHEMBL7958294 | 0.70 | — | — | |
| SCHEMBL3062309 | 0.68 | — | — | |
| SCHEMBL10424750 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2131656-A2 | PHTHALAZINE DERIVATIVES | Forest Laboratories Holdings Limited (BM) | 2009-12-16 | — | — | EP | claimed |
| WO-2008061108-A2 | PHTHALAZINE DERIVATIVES | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-05-22 | — | — | WO | claimed |
| US-4552888-A | Ascorbic acid ethers in angiogene | ELI LILLY AND COMPANY (US) | 1985-11-12 | — | — | US | disclosed |
| EP-0086554-A1 | Ascorbic acid ethers and related compounds | ELI LILLY AND COMPANY (US) | 1983-08-24 | — | — | EP | disclosed |