SCHEMBL5071955

SCHEMBL5071955

Cc1cc(S(=O)(=O)c2cc(C)c(C(=O)O)c(C(=O)O)c2)cc(C(=O)O)c1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.41
ACHE P22303 1/20 0.41
LMNA P02545 3/20 0.40
MAPT P10636 1/20 0.40
ALDH1A1 P00352 4/20 0.39
MAPK1 P28482 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
POLB P06746 2/20 0.37
APEX1 P27695 1/20 0.37
CTDSP1 Q9GZU7 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
METAP2 P50579 1/20 0.37
KDM4E B2RXH2 4/20 0.37
HSD17B10 Q99714 3/20 0.37
HPGD P15428 2/20 0.37
PLA2G2A P14555 1/20 0.36
NOTUM Q6P988 1/20 0.36
GAA P10253 2/20 0.36
TSHR P16473 1/20 0.36
MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30263035 0.78 KDM4E (0.59) CYP3A4ACHELMNAMAPTALDH1A1
SCHEMBL4659030 0.75 MCL1 (0.48) CYP3A4ACHEMAPTALDH1A1MAPK1
SCHEMBL3387328 0.75 KDM4E (0.61) CYP3A4ACHELMNAMAPTALDH1A1
SCHEMBL15746904 0.74 POLB (0.54) LMNAMAPTALDH1A1SMN1; SMN2POLB
SCHEMBL2807317 0.74 APEX1 (0.53) LMNAMAPTALDH1A1SMN1; SMN2POLB
SCHEMBL16468693 0.74 LCK (0.54) CYP3A4ACHELMNAMAPTALDH1A1
SCHEMBL9353947 0.74 CYP3A4 (0.67) CYP3A4ACHELMNAMAPTALDH1A1
SCHEMBL6334301 0.74 TPMT (0.48) CYP3A4ACHEMAPTALDH1A1MAPK1
SCHEMBL4132949 0.73 PHLPP2 (0.52) LMNAMAPTALDH1A1L3MBTL1METAP2
SCHEMBL2529829 0.73 CYP3A4 (0.48) CYP3A4ACHELMNAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100462389-C Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS INC (JP) 2009-02-18 CN disclosed
US-7345135-B2 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2008-03-18 US disclosed
CN-1630676-A Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS INC (JP) 2005-06-22 CN disclosed